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  2. Opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic

    With the increase in volume, the potency of opioids also increased. By 2002, one in six drug users were being prescribed drugs more powerful than morphine; by 2012, the ratio had doubled to one in three. [18] The most commonly prescribed opioids have been oxycodone and hydrocodone. The epidemic has been described as a "uniquely American problem ...

  3. Pain ladder - Wikipedia

    en.wikipedia.org/wiki/Pain_ladder

    "Pain ladder", or analgesic ladder, was created by the World Health Organization (WHO) as a guideline for the use of drugs in the management of pain. Originally published in 1986 for the management of cancer pain , it is now widely used by medical professionals for the management of all types of pain .

  4. Timeline of the opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_the_opioid...

    1911 - 1990s According to the FDA's Timeline of Selected FDA Activities and Significant Events Addressing Opioid Misuse and Abuse, before the 1990s, most opioid pain medications were used to manage pain that was either acute or related to cancer. The FDA said that there was an increase in the use of opioids because physicians were not treating ...

  5. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Diversion, abuse, and a relatively high rate of overdose deaths in comparison to other drugs of its group. This drug continues to be available in most of the world including the US, but under strict controls. Terfenadine (Seldane, Triludan) 1997–1998 France, South Africa, Oman, others, US Prolonged QT interval; ventricular tachycardia [2] [3]

  6. Oxycodone/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Oxycodone/paracetamol

    Oxycodone/paracetamol, sold under the brand name Percocet among others, [2] is a fixed-dose combination of the opioid oxycodone with paracetamol (acetaminophen), used to treat moderate to severe pain. [1] In 2022, it was the 98th most commonly prescribed medication in the United States, with more than 6 million prescriptions. [3] [4]

  7. FDA approves opioid-free pain medication with 'no sign of ...

    www.aol.com/fda-approves-opioid-free-pain...

    A new opioid-free pain medication was approved by the U.S. Food and Drug Administration (FDA) on Thursday, marking a non-addictive alternative for patients. Journavx (suzetrigine), made by Vertex ...

  8. Phenacetin - Wikipedia

    en.wikipedia.org/wiki/Phenacetin

    Phenacetin (/ f ɪ ˈ n æ s ɪ t ɪ n / ⓘ; acetophenetidin, N-(4-ethoxyphenyl)acetamide [1]) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887. It was withdrawn from medicinal use as dangerous from the 1970s (e.g., withdrawn in Canada in 1973, [2] and by the U.S. Food and Drug ...

  9. Tuinal - Wikipedia

    en.wikipedia.org/wiki/Tuinal

    It was reported in the 1980s as one of the most common ways of self-poisoning. [7] Abuse of this particular drug tapered off after it was discontinued by manufacturers in the late 1990s. Tuinal is classified as a Schedule II drug under the Controlled Substances Act in the United States, meaning it requires a prescription from a licensed ...

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