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For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP ...
Galactose-α-1,3-galactose, commonly known as alpha gal and the Galili antigen, is a carbohydrate found in most mammalian cell membranes. It is not found in catarrhines , [ 1 ] including humans, who have lost the glycoprotein alpha-1,3-galactosyltransferase ( GGTA1 ) gene.
Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), [1] is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002.
DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase (EC 2.6.1.90, dTDP-6-deoxy-D-xylohex-3-uloseaminase, FdtB, TDP-3-keto-6-deoxy-D-galactose-3-aminotransferase, RavAMT, TDP-3-keto-6-deoxy-D-galactose 3-aminotransferase, TDP-3-dehydro-6-deoxy-D-galactose 3-aminotransferase) is an enzyme with systematic name dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose:2-oxoglutarate ...
For infants with DG who showed elevated galactose metabolites at diagnosis, this test can be used to see if the child's ability to process galactose has improved. [citation needed] For example, to test galactose metabolism, a baseline Gal-1P level is measured while the child is on a galactose-restricted diet.
Galactokinase is an enzyme (phosphotransferase) that facilitates the phosphorylation of α-D-galactose to galactose 1-phosphate at the expense of one molecule of ATP. [1] Galactokinase catalyzes the second step of the Leloir pathway, a metabolic pathway found in most organisms for the catabolism of α-D-galactose to glucose 1-phosphate. [2]
A segment of galactomannan showing mannose backbone (below) with a branching galactose unit (top) Galactomannans are polysaccharides consisting of a mannose backbone with galactose side groups, more specifically, a (1-4)-linked beta-D-mannopyranose backbone with branchpoints from their 6-positions linked to alpha-D-galactose, (i.e. 1-6-linked alpha-D-galactopyranose).
The systematic name of this enzyme class is UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase. Other names in common use include uridine diphosphogalactose-lactosylceramide , and beta1->3-galactosyltransferase .