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Electronic health records, [87] [88] [54] death certificates [89] [56] [90] [91] as well as post-mortem analyses (such as post-mortem computed tomography and other other pathology) [92] can and are often used to investigate underlying causes of deaths such as for mortality statistics, [93] [94] relevant to progress measurements. [95]
The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]
Exposure to high levels of dioxins in humans causes a severe form of persistent acne, known as chloracne. [34] High occupational or accidental levels of exposures to dioxins have been shown by epidemiological studies to lead to an increased risk of tumors at all sites. [35] Other effects in humans (at high dose levels) may include:
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
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In law, medicine, and statistics, cause of death is an official determination of the conditions resulting in a human's death, which may be recorded on a death certificate. A cause of death is determined by a medical examiner. In rare cases, an autopsy needs to be performed by a pathologist. The cause of death is a specific disease or injury, in ...
Vital statistics generally distinguish specific injuries and diseases as cause of death, from general categories like homicide, accident, and death by natural causes as manner of death. Both are listed in this category, as are both proximal and root causes of death. An injury that could be fatal is called major trauma; see also Category:Injuries.