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A bone scan or bone scintigraphy / s ɪ n ˈ t ɪ ɡ r ə f i / is a nuclear medicine imaging technique used to help diagnose and assess different bone diseases. These include cancer of the bone or metastasis, location of bone inflammation and fractures (that may not be visible in traditional X-ray images), and bone infection (osteomyelitis). [1]
Amyloid deposition in aortic stenosis shown by DPD scan. A DPD scan is a type of nuclear medicine imaging test which uses radioactive technetium-99m (99m Tc) and 3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) to diagnose cardiac amyloidosis.
The signal transfer function (SiTF) is a measure of the signal output versus the signal input of a system such as an infrared system or sensor. There are many general applications of the SiTF. Specifically, in the field of image analysis, it gives a measure of the noise of an imaging system, and thus yields one assessment of its performance. [1]
SPECT image (bone tracer) of a mouse MIP Collimator used to collimate gamma rays (red arrows) in a gamma camera. Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique using gamma rays. [1]
A gamma camera consists of one or more flat crystal planes (or detectors) optically coupled to an array of photomultiplier tubes in an assembly known as a "head", mounted on a gantry. The gantry is connected to a computer system that both controls the operation of the camera and acquires and stores images.
Technetium (99m Tc) sestamibi (commonly sestamibi; USP: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in nuclear medicine imaging.The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) ligands.
A skeletal survey (also called a bone survey [1]) is a series of X-rays of all the bones in the body, or at least the axial skeleton and the large cortical bones. A very common use is the diagnosis of multiple myeloma , where tumour deposits appear as "punched-out" lesions.
DXA BMD results adjusted in this manner are referred to as the bone mineral apparent density (BMAD) and are a ratio of the bone mineral content versus a cuboidal estimation of the volume of bone. Like the results for aBMD, BMAD results do not accurately represent true bone mineral density, since they use approximations of the bone's volume.