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RKI-1447 is a drug which acts as a potent and selective inhibitor of the enzyme Rho kinase, with an IC 50 of 14.5 nM at ROCK1 and 6.2 nM at ROCK2. It has been investigated for applications in cancer treatment, [ 1 ] [ 2 ] [ 3 ] as well as glaucoma , [ 4 ] and nonalcoholic fatty liver disease .
The Robert Koch Institute (RKI) is a German federal government agency and research institute responsible for disease control and prevention. It is located in Berlin and Wernigerode . As an upper federal agency, it is subordinate to the Federal Ministry of Health .
The Yaesu VX series is a line of two sequences of compact amateur radio handheld transceivers produced by Yaesu.There is a line of ultra-compact lower-power dual-band (2 m and 70 cm) transceivers that started with the VX-1R and was later updated with the VX-2R and VX-3R.
Hints for Today's Connections Sports Edition Categories on February 21, 2025. Here are some hints about the four categories to help you figure out the word groupings.
The first all-new GX in over a decade is here, and it looks great. Take a look at the new two-tone paint scheme, 33-inch tires, and redesigned interior. 2024 Lexus GX 550 - Photos From Every Angle
TILE-Gx was a VLIW ISA multicore processor family designed by Tilera. It consisted of a mesh network [7] that was expected to scale up to 100 cores, [8] but only 72-core variants actually shipped. [9] After a few acquisitions, Tilera's designs ended up in the hands of Nvidia, which ended production of TILE-Gx processors in 2022. [1]
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