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Cell fusion is an important cellular process in which several uninucleate cells (cells with a single nucleus) combine to form a multinucleate cell, known as a syncytium. Cell fusion occurs during differentiation of myoblasts, osteoclasts and trophoblasts, during embryogenesis, and morphogenesis. [1] Cell fusion is a necessary event in the ...
Mitochondrial fusion. Mitochondria are dynamic organelles with the ability to fuse and divide (fission), forming constantly changing tubular networks in most eukaryotic cells. These mitochondrial dynamics, first observed over a hundred years ago [1] are important for the health of the cell, and defects in dynamics lead to genetic disorders.
Hybridoma technology is a method for producing large numbers of identical antibodies, also called monoclonal antibodies. This process starts by injecting a mouse (or other mammal) with an antigen that provokes an immune response. A type of white blood cell, the B cell, produces antibodies that bind to the injected antigen.
Hybrid cell line. A hybrid cell line is a fusion of cells from two different cell types. When the membrane of two cells merge, the nuclei combine to form a polykaryote (poly- multiple; karyon- chromosome ). [1] These fusions can happen spontaneously as in the case of tumor hybrid cells, or may be induced by a variety of laboratory techniques.
In full fusion both leaflets as well as the internal contents mix. In membrane biology, fusion is the process by which two initially distinct lipid bilayers merge their hydrophobic cores, resulting in one interconnected structure. If this fusion proceeds completely through both leaflets of both bilayers, an aqueous bridge is formed and the ...
HAT selection depicted by a plasmacytoma thymidine kinase mutant fused with a mortal splenic B-cell.. HAT Medium (hypoxanthine-aminopterin-thymidine medium) is a selection medium for mammalian cell culture, which relies on the combination of aminopterin, a drug that acts as a powerful folate metabolism inhibitor by inhibiting dihydrofolate reductase, with hypoxanthine (a purine derivative) and ...
A genetic chimerism or chimera (/ kaɪˈmɪərə / ky-MEER-ə or / kɪˈmɪərə / kim-EER-ə) is a single organism composed of cells with more than one distinct genotype. Animal chimeras can be produced by the merger of two (or more) embryos. In plants and some animal chimeras, mosaicism involves distinct types of tissue that originated from ...
Diagrammatic. "Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there. It is interior to the syncytiotrophoblast and external to the wall of the blastocyst in a developing embryo. The cytotrophoblast is considered to be the trophoblastic stem cell because the ...