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A continuum of M1-M2 polarization may arise even in the absence of polarizing cytokines and differences in substrate stiffness. [4] M1 macrophages were described as the pro-inflammatory type, important in direct host-defense against pathogens, such as phagocytosis and secretion of pro-inflammatory cytokines and microbicidal molecules. M2 ...
The MacBook Air is a line of Mac laptops made by Apple Inc. In 2020, Apple stopped using Intel processors in the Air and switched to using their own Apple silicon M-series chips. In the current product line, the MacBook Air is Apple's entry-level laptop, situated below the performance range MacBook Pro, and is currently sold with 13-inch and 15 ...
Both have 12 CPU cores (8 performance and 4 efficiency) and a 16-core Neural Engine. The M2 Pro and M2 Max have a 19-core and 38-core GPU, and a 256-bit and 512-bit LPDDR5 memory bus supporting 200 and 400 GB/s bandwidth respectively. Both chips were first introduced in the MacBook Pro in January 2023.
On October 30, 2018, Apple released a new MacBook Air with Amber Lake processors, a 13.3-inch Retina display with a resolution of 2560×1600 pixels, Touch ID, and two combination USB-C 3.1 Gen 2/ Thunderbolt 3 ports plus one audio jack. The screen displays 48% more color, and the bezels are 50% narrower than the previous generation and occupies ...
Mac Pro (replacing the Power Mac G5) launched August 7, 2006. MacBook (replacing the iBook) launched May 16, 2006. MacBook Pro (replacing the PowerBook G4) launched February 26, 2008. iMac Aluminum, launched April 28, 2008. MacBook Air Unibody, launched January 15, 2008. MacBook Aluminum Unibody, launched June 8, 2009.
v. t. e. Apple M1 is a series of ARM -based system-on-a-chip (SoC) designed by Apple Inc., part of the Apple silicon series, as a central processing unit (CPU) and graphics processing unit (GPU) for its Mac desktops and notebooks, and the iPad Pro and iPad Air tablets. [ 4] The M1 chip initiated Apple's third change to the instruction set ...
Unlike M1 macrophages, M2 macrophages secrete an anti-inflammatory response via the addition of Interleukin-4 or Interleukin-13. They also play a role in wound healing and are needed for revascularization and reepithelialization. M2 macrophages are divided into four major types based on their roles: M2a, M2b, M2c, and M2d.
M1 macrophages are seen to have a pro-inflammatory and cytotoxic (anti-tumoral) function; M2 macrophages are anti-inflammatory (pro-tumoral) and promote wound healing. However, use of the M1/M2 polarization paradigm has led to confusing terminology since M1/M2 are used to describe mature macrophages, but the activation process is complex and ...
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