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2. Opioid-Induced Hyperalgesia: How Opioids Can Increase Pain - HSS

   www.hss.edu/conditions_opioid-induced-hyperalgesia.asp

   What are the symptoms of opioid-induced hyperalgesia? A lot is going on in the body when we are injured. Simultaneously, our bodies are trying to repair the damaged tissue, stop bleeding, prevent infection, and keep us moving and safe from other threats.

3. A comprehensive review of opioid-induced hyperalgesia

   pubmed.ncbi.nlm.nih.gov/21412369

   Opioid-induced hyperalgesia (OIH) is defined as a state of nociceptive sensitization caused by exposure to opioids. The condition is characterized by a paradoxical response whereby a patient receiving opioids for the treatment of pain could actually become more sensitive to certain painful stimuli. ….

4. Opioid-induced hyperalgesia - Wikipedia

   en.wikipedia.org/wiki/Opioid-induced_hyperalgesia

   Opioid-induced hyperalgesia (OIH) or opioid-induced abnormal pain sensitivity, also called paradoxical hyperalgesia, is an uncommon condition of generalized pain caused by the long-term use of high dosages of opioids [1] such as morphine, [2] oxycodone, [3] and methadone.

5. Mechanisms, diagnosis, prevention and management of perioperative...

   pmc.ncbi.nlm.nih.gov/articles/PMC8023328

   Opioid-induced hyperalgesia (OIH) occurs when opioids paradoxically enhance the pain they are prescribed to ameliorate. To address a lack of perioperative awareness, we present an educational review of clinically relevant aspects of the disorder.

6. Opioid-Induced Hyperalgesia: Symptoms, Treatment, Outlook, and...

   www.healthline.com/health/hyperalgesia

   When a person becomes more sensitive to pain as a result of taking opioid medication, it’s called opioid-induced hyperalgesia (OIH). Due to the increase in opioid usage, OIH is becoming more of a...

7. Opioid-induced Hyperalgesia | Anesthesiology | American Society...

   pubs.asahq.org/.../article/104/3/570/8782/Opioid-induced-HyperalgesiaA-Qualitative

   In this systematic review, we divided opioid-induced hyperalgesia into three major categories based on the opioid dose and further subdivided these categories by distinguishing various types of pain as well as route and pattern of opioid administration.

8. More opioids, more pain: Fueling the fire - Harvard Health

   www.health.harvard.edu/blog/more-opioids-more-pain-fueling-the-fire-2019070817024

   Research studies and clinical observations over the years have identified the phenomenon Dr. Allbutt noticed as opioid-induced hyperalgesia (OIH). What is opioid-induced hyperalgesia? Hyperalgesia is an increased pain response from a stimulus (cause) that usually provokes a minor pain response.

9. Opioid Induced Hyperalgesia | Pain Medicine | Oxford Academic

   academic.oup.com/painmedicine/article/16/suppl_1/S32/2472483

   Opioid induced hyperalgesia (OIH) is a state of enhanced pain sensitization in patients who are on chronic opioid therapy (COT). Historically, the phenomenon of OIH has been described as early as the 19th century.

10. Pharmacological Interventions for Opioid-Induced Hyperalgesia: A...

    pmc.ncbi.nlm.nih.gov/articles/PMC9735807

    One of the lesser-known limitations is opioid-induced hyperalgesia (OIH), which refers to the increased pain sensitivity that occurs once analgesia wears off after opioid administration . OIH is commonly measured by quantitative sensory testing (QST), where mechanical or thermal stimuli are used to assess the subject’s pain threshold [ 3 ].

11. A Comprehensive Review of Opioid-Induced Hyperalgesia

    www.painphysicianjournal.com/current/pdf?article=MTQ0Ng==&journal=60

    Opioid-induced hyperalgesia (OIH) is defined as a state of nociceptive sensitization caused by exposure to opioids. The condition is characterized by a paradoxical response whereby a patient receiving opioids for the treatment of pain could actually become more sensitive to certain painful stimuli. The type of pain experienced might be the