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Uterine contraction. Uterine contractions are muscle contractions of the uterine smooth muscle that can occur at various intensities in both the non-pregnant and pregnant uterine state. The non-pregnant uterus undergoes small, spontaneous contractions in addition to stronger, coordinated contractions during the menstrual cycle and orgasm.
In either form, oxytocin stimulates uterine contractions to speed up the process of childbirth. In its natural form, it also plays a role in maternal bonding and milk production. [10] [11] Production and secretion of oxytocin is controlled by a positive feedback mechanism, where its initial release stimulates production and release of further ...
Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium of the uterus at the end of pregnancy. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection.
The area of action differs for each effect, contraction occurs in the upper uterine segment while relaxation occurs in the lower uterine segment. [14] Not as efficacious for inducing labor when compared to other prostaglandins. [16] Dinoprost: also known as PGF 2α, is a naturally occurring prostaglandin which causes contraction via PG F ...
During human parturition, the quantifiable level of blood plasma oxytocin rises: it becomes twice as much during the initial phase of dilation and continues to increase until the second stage of labor. [36] Oxytocin furthermore induces uterine contractions in mothers following childbirth which helps in the prevention of bleeding. [37]
The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus. It has a basal layer and a functional layer: the basal layer contains stem cells which regenerate the functional layer. [1] The functional layer thickens and then is shed during menstruation in humans and some other mammals, including other ...
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Labor is characterized by uterine contractions which push the fetus through the birth canal and results in delivery. [14] Labor is divided into three stages. First stage of labor starts with the onset of contractions and finishes when the cervix is fully dilated at 10 cm. [15] This stage can further be divided into latent and active labor. The ...