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Aducanumab, sold under the brand name Aduhelm, is an anti-amyloid drug designed to treat Alzheimer's disease. [2] [3] It is a monoclonal antibody [3] [2] that targets aggregated forms (plaque) [4] [5] of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup.
Aducanumab, sold under the brand name Aduhelm, is an anti-amyloid drug designed to treat Alzheimer's disease. It is a monoclonal antibody that targets aggregated forms (plaque) of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup. [10] It was developed by Biogen and Eisai. [11] Aducanumab is given via intravenous infusion. [5] Aducanumab was ...
A skull showing evidence of trepanning. Prehistoric medicine is any use of medicine from before the invention of writing and the documented history of medicine.Because the timing of the invention of writing per culture and region, the term "prehistoric medicine" encompasses a wide range of time periods and dates.
Detail from The Extraction of the Stone of Madness, a painting by Hieronymus Bosch depicting trepanation (c. 1488–1516). Trepanning, also known as trepanation, trephination, trephining or making a burr hole (the verb trepan derives from Old French from Medieval Latin trepanum from Greek trúpanon, literally "borer, auger"), [1] [2] is a surgical intervention in which a hole is drilled or ...
The exact pathophysiological causes of the disease are currently unclear, but there are developing theories. [8] Spongy degeneration can be diagnosed with neuroimaging techniques and urine examination. [9] There is no current treatment for spongy degeneration, but research utilising gene therapy to treat the disease is underway. [8]
While it was once “just” a medication for people with type 2 diabetes, metformin is now thought of as a “wonder drug with multiple potentials,” says David Cutler, M.D., a family medicine ...
Psilocybe cubensis mushrooms in Coyopolan, Veracruz, Mexico.McKenna and his proponents place these psilocybin mushrooms as the central force in the theory. The stoned ape theory is a controversial hypothesis first proposed by American ethnobotanist and mystic Terence McKenna in his 1992 book Food of the Gods.
These ICV injections result in models for the sporadic Alzheimer's disease (sAD) form, rather than familial. A characteristic of sAD is an insulin-resistant brain state (IRBS). Streptozotocin is a beta-cytotoxic drug and by injecting it directly into the cerebral ventricles, the treated mice develop symptoms that align with sAD symptoms in humans.