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Frontal fibrosing alopecia is the frontotemporal hairline recession and eyebrow loss in postmenopausal women that is associated with perifollicular erythema, especially along the hairline. [ 2 ] [ 3 ] : 648 It is considered to be a clinical variant of lichen planopilaris .
Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE) [1] or post-exertional neuroimmune exhaustion (PENE), [2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...
Fibromyalgia is estimated to affect 2 to 4% of the population. [13] Women are affected more than men. [4] [13] Rates appear similar across areas of the world and among varied cultures. [4] Symptoms of fibromyalgia are persistent in nearly all patients. [14] The treatment of fibromyalgia is symptomatic [15] and multidisciplinary. [16]
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
The primary age range is 15–60, with a peak between 30 and 40 years old; it is 2–3 times more common in females than males. [ 1 ] [ 8 ] [ 18 ] A 2012 retrospective multi-institutional analysis of 211 patients found a median age of 36 and a 68% female prevalence. [ 19 ]
For example, some autoimmune diseases tend to flare during pregnancy (possibly as an evolutionary mechanism to increase health protection for the child), [50] when hormone levels are high, and improve after menopause, when hormone levels decrease. Women may also naturally have autoimmune disease trigger events in puberty and pregnancy. [48]
They first met in 1997 through discussions in online fibromyalgia chat groups, and shared similar concerns over incorrect diagnoses as well as a lack of available information and patient support. [6] Matallana had first experienced symptoms of pain and fatigue in 1993, and by 1997 had visited 37 doctors before being diagnosed with fibromyalgia.
Per Jens J. Pindborg and Satyavati Sirsat (1966, pathological definition): 'An insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx. . Although occasionally preceded by and/or associated with vesicle formation, it is always associated with a juxta-epithelial inflammatory reaction followed by a fibro-elastic change of the lamina propria, with epithelial ...
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