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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone is commonly used in the treatment of hirsutism in women, and is considered to be a first-line antiandrogen for this indication. [68] Spironolactone can be used in the treatment of female-pattern hair loss (pattern scalp hair loss in women). [69] There is tentative low quality evidence supporting its use for this indication. [70]

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Canrenone is an antagonist of the MR as is spironolactone, [25] but it is slightly more potent in comparison. [ 24 ] [ 26 ] It has been determined that 7α-TMS accounts for around 80% of the potassium-sparing effect of spironolactone [ 1 ] [ 2 ] [ 3 ] while canrenone accounts for the remaining approximately 10 to 25%. [ 4 ]

  4. Potassium-sparing diuretic - Wikipedia

    en.wikipedia.org/wiki/Potassium-sparing_diuretic

    They are typically used as an adjunct in management of hypertension, cirrhosis, and congestive heart failure. [3] The steroidal aldosterone antagonists can also be used for treatment of primary hyperaldosteronism. Spironolactone, a steroidal aldosterone antagonist, is also used in management of female hirsutism and acne from PCOS or other ...

  5. Does Low Estrogen Cause Hair Loss? - AOL

    www.aol.com/does-low-estrogen-cause-hair...

    Some medications, including those used in breast cancer treatment and prevention, work by reducing the amount of estrogen produced by your body. ... (0.25 to 2.5 mg daily). Spironolactone.

  6. RALES (trial) - Wikipedia

    en.wikipedia.org/wiki/RALES_(trial)

    The trial was stopped early because the beneficial effect of spironolactone on all-cause death exceeded the prespecified discontinuation requirements. Spironolactone reduced the risk of death by 30% compared to placebo. Additionally, there was a 35% reduction in the risk of hospitalization for worsening heart failure in the spironolactone group.

  7. FDA approves new pain medication as an alternative to opioids ...

    www.aol.com/fda-approves-pain-medication...

    Vertex Pharmaceuticals claimed in a press release that the medication can be used for many types of moderate-to-severe acute pain and ... Giddey scores 25 points as the Bulls snap a 6-game skid ...

  8. “An anti-inflammatory diet is the selection of foods that reduce the chronic inflammatory response, while at the same time providing the building blocks for use by anti-inflammatory pathways ...

  9. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    Spironolactone, the first member of the class, is also used in the management of hyperaldosteronism (including Conn's syndrome) and female hirsutism (due to additional antiandrogen actions). Most antimineralocorticoids, including spironolactone, are steroidal spirolactones. Finerenone is a nonsteroidal antimineralocorticoid.

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