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While use during pregnancy is not recommended, risk appears to be low. [6] The use of other medications in this class appear to be safe while breastfeeding; however, the safety of levofloxacin is unclear. [6] Levofloxacin was patented in 1985 and approved for medical use in the United States in 1996.
PPI (standard dose) bid, tetracycline 0.5 g qid, metronidazole 0.25 g qid and bismuth standard dose qid First line or second line therapy Levofloxacin-based triple therapy 10 PPI (standard dose) bid, levofloxacin 0.5 g qd and amoxicillin 1 g bid Second line therapy if there is no fluoroquinolone resistance Culture-guided therapy 10
The Mercer protocol is a common regimen for antibiotic prophylaxis in the context of preterm premature rupture of membranes (PPROM) during pregnancy, when immediate delivery is contraindicated due to known or suspected fetal lung immaturity.
Safety concerns exist for fluoroquinolone use during pregnancy, so they are contraindicated unless no other safe alternative antibiotic exists. [54] However, one meta-analysis looking at the outcome of pregnancies involving quinolone use in the first trimester found no increased risk of malformations. [ 55 ]
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy.It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk.
Complications of Pregnancy, Childbirth, and the Puerperium XII 680–709: Diseases of the Skin and Subcutaneous Tissue XIII 710–739: Diseases of the Musculoskeletal System and Connective Tissue XIV 740–759: Congenital Anomalies XV 760–779: Certain Conditions originating in the Perinatal Period XVI 780–799: Symptoms, Signs and Ill ...
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
Plates vi & vii of the Edwin Smith Papyrus (around the 17th century BC), among the earliest medical guidelines. A medical guideline (also called a clinical guideline, standard treatment guideline, or clinical practice guideline) is a document with the aim of guiding decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare.