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Colocalization is used in real-time single-molecule fluorescence microscopy to detect interactions between fluorescently labeled molecular species. In this case, one species (e.g. a DNA molecule) is typically immobilized on the imaging surface, and the other species (e.g. a DNA-binding protein) is supplied to the solution.
Colocalization is a visual phenomenon when two molecules of interest are associated with the same structures in the cells and potentially share common functional characteristics. [1] [2] [3] CBS provides researchers with reference tools to verify the results of quantitative colocalization measurements. [4]
These structures correspond in size and location to the fluorescent bodies confirmed to be scintillons by their light emission, and they show colocalization of anti-luciferase and anti-LBP labeling meaning both bioluminescence proteins are found in the structures. [8]
Transcription activator-like (TAL) Effector-Nucleotide Targeter 2.0 (TALE-NT) is a suite of web-based tools that allows for custom design of TAL effector repeat arrays for desired targets and prediction of TAL effector binding sites.
The morphometric method is a way to demonstrate cell death in the laboratory. Morphometric measurement provides the result of cell death as a volume, size, weight and length of tissue, organ and the whole organism that compares with before and after the occurrence of cell death. [2]
Dlx3 is a crucial regulator of hair follicle differentiation and cycling. Dlx3 transcription is mediated through Wnt, and colocalization of Dlx3 with phospho-SMAD1/5/8 is involved in the regulation of transcription by BMP signaling. [7] Dlx3 transcription is also induced by BMP-2 through transactivation with SMAD1 and SMAD4. [8]
The image above depicts the conversion from a cosegregation matrix to an adjacency matrix is one use of a matrix in genome architecture mapping where scientists are using cryosectioning to find colocalization between DNA regions, genomes, and/or alleles. In that example, cosegregation is being used to describe the linkage of data to each other ...
110862 Ensembl ENSG00000184156 ENSMUSG00000056258 UniProt O43525 Q8K3F6 RefSeq (mRNA) NM_001204824 NM_004519 NM_152923 RefSeq (protein) NP_001191753 NP_004510 NP_690887 Location (UCSC) Chr 8: 132.12 – 132.48 Mb Chr 15: 65.86 – 66.16 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse K v 7.3 (KvLQT3) is a potassium channel protein coded for by the gene KCNQ3. It is associated with ...