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In the research commentary, the authors wrote that up to one-third of kratom users experience an adverse side effect. A 2022 study links kratom use to multiple adverse events, including: cardiac ...
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
The FDA is aware of 36 deaths linked to the drug, as well as a tenfold increase in calls to poison control centers about the substance from 2010 to 2015.
The Journal of Substance Use and Addiction Treatment (JSAT; formerly Journal of Substance Abuse Treatment [1]) is a peer-reviewed medical journal covering research on substance use and drug addiction, and the treatment of such disorders. It was established in 1984 and is currently published monthly by Elsevier. The editor-in-chief is Hannah K ...
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]
Addiction is a monthly peer-reviewed scientific journal established in 1903 by the Society for the Study of Addiction to Alcohol and other Drugs as the British Journal of Inebriety. It was renamed British Journal of Addiction to Alcohol & Other Drugs in 1947, then renamed to British Journal of Addiction in 1980, before finally obtaining its ...
There’s no single explanation for why addiction treatment is mired in a kind of scientific dark age, why addicts are denied the help that modern medicine can offer. Family doctors tend to see addicts as a nuisance or a liability and don’t want them crowding their waiting rooms. In American culture, self-help runs deep.