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The term "phaeohyphomycosis" was introduced to determine infections caused by dematiaceous (pigmented) filamentous fungi which contain melanin in their cell walls. [11] Phaeohyphomycosis is an uncommon infection, but the number of cases reported has been increasing in recent years. Fungal melanin is thought to be a virulence factor.
In the absence of radiation, some non-melanized fungi (that had been mutated in the melanin pathway) grew faster than their melanized counterparts. Limited uptake of nutrients due to the melanin molecules in the fungal cell wall or toxic intermediates formed in melanin biosynthesis have been suggested to contribute to this phenomenon. [6]
Melanin (/ ˈ m ɛ l ə n ɪ n / ⓘ; from Ancient Greek μέλας (mélas) 'black, dark') is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. [1] Melanin pigments are produced in a specialized group of cells known as melanocytes.
Aureobasidium melanogenum, formerly known as Aureobasidium pullulans var. melanogenum is a ubiquitous black, yeast-like fungus that is found mainly in freshwater habitats. . The species also includes strains causing human infections, which were previously classified as A. pullulans
Cladophialophora bantiana (C. bantiana) is a melanin producing mold known to cause brain abscesses in humans. [1] It is one of the most common causes of systemic phaeohyphomycosis in mammals. [ 2 ] Cladophialophora bantiana is a member of the ascomycota and has been isolated from soil samples from around the world.
Both molecules are responsible for the characteristic dark grain color. The melanin produced by the fungus has also been identified as a defense mechanism against processes such as hydrolytic enzymes, free radicals, redox buffering, antibodies and complement. [10] The fungus also produces pyomelanin, a brown diffusible pigment. [3]
Presence of 1,8-dihydroxynaphthalene melanin in the cell wall [9] confers to the microfungi their characteristic olivaceous to dark brown/black colour. The consortium comprises two phylogenetically very different fungal groups. [10] [11] Many are found in the orders Capnodiales, Dothideales, and Pleosporales (class Dothideomycetes). These black ...
The English word fungus is directly adopted from the Latin fungus (mushroom), used in the writings of Horace and Pliny. [10] This in turn is derived from the Greek word sphongos (σφόγγος 'sponge'), which refers to the macroscopic structures and morphology of mushrooms and molds; [11] the root is also used in other languages, such as the German Schwamm ('sponge') and Schimmel ('mold').