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The level of activity that triggers PEM, as well as the symptoms, vary from person to person, and within individuals over time. [6] Due to this variability, affected people may be unable to predict what will trigger it. [4] This variable, relapsing-remitting pattern can cause one's abilities to fluctuate from one day to the next. [1]
Fibromyalgia (FM) is a medical syndrome that causes chronic widespread pain, accompanied by fatigue, awakening unrefreshed, and cognitive symptoms. Other symptoms can include headaches , lower abdominal pain or cramps , and depression . [ 9 ]
Myofascial trigger points (MTrPs), also known as trigger points, are described as hyperirritable spots in the skeletal muscle. They are associated with palpable nodules in taut bands of muscle fibers. [1] They are a topic of ongoing controversy, as there is limited data to inform a scientific understanding of the phenomenon.
The North Central Cancer Treatment Group (NCCTG) is an international clinical research group sponsored by the National Cancer Institute. The NCCTG consists of a network of cancer specialists at community clinics, hospitals and medical centers in the United States , Canada and Mexico .
Amplified musculoskeletal pain is a syndrome which is a set of characteristic symptoms and signs. Essentially, the syndrome is characterized by diffuse, ongoing, daily pain associated with relatively high levels of incapability and greater care-seeking behavior.
For instance, research suggests that the bacterium that causes strep throat, Streptococcus pyogenes, might trigger rheumatic fever, an autoimmune response affecting the heart. [58] Similarly, some studies propose a link between the Epstein–Barr virus, responsible for mononucleosis, and the subsequent development of multiple sclerosis or lupus.
Fibromyalgia is a disorder in which an individual experiences dysfunctional brain activity, musculoskeletal pain, fatigue, and tenderness in localized areas. [20] Research examining tDCS for pain treatment in fibromyalgia has found initial evidence for pain decreases. [20]
The International Association for the Study of Pain (IASP) defines chronic pain as a general pain without biological value that sometimes continues even after the healing of the affected area; [8] [9] a type of pain that cannot be classified as acute pain [b] and lasts longer than expected to heal, or typically, pain that has been experienced on most days or daily for the past six months, is ...
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