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  2. 2008 Chinese heparin adulteration - Wikipedia

    en.wikipedia.org/wiki/2008_Chinese_heparin...

    The raw material for the recalled heparin batches was processed in China from pig's intestines by the American pharmaceutical firm Scientific Protein Laboratories. [1] [2] [3] The U.S. Food and Drug Administration was quoted as stating that at least 81 deaths were believed to be linked to a raw heparin ingredient imported from the People's Republic of China, and that they had also received 785 ...

  3. Heparin - Wikipedia

    en.wikipedia.org/wiki/Heparin

    Heparin production experienced a break in the 1990s. Until then, heparin was mainly obtained from cattle tissue, which was a by-product of the meat industry, especially in North America. With the rapid spread of BSE, more and more manufacturers abandoned this source of supply. As a result, global heparin production became increasingly ...

  4. Discovery and development of direct thrombin inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    In the 1980s low molecular-weight heparin (LMWH) were developed. They are derived from heparin by enzymatic or chemical depolymerization and have better pharmacokinetic properties than heparin. In 1955 the first clinical use of warfarin, a vitamin K antagonist, was reported. Warfarin was originally used as a rat poison in 1948 and thought to be ...

  5. Timeline of Chinese history - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_Chinese_history

    Timeline of Chinese history. This is a timeline of Chinese history, comprising important legal and territorial changes and political events in China and its dynasties. To read about the background to these events, see History of China. See also the list of Chinese monarchs, Chinese emperors family tree, dynasties of China and years in China.

  6. 2008 in China - Wikipedia

    en.wikipedia.org/wiki/2008_in_China

    May. A 7.9-magnitude earthquake in Sichuan, China killed nearly 88,000 people. May 11 – China Commercial Aircraft Corporation (COMAC) was founded. [citation needed] May 12 – 2008 Sichuan earthquake: Over 70,000 killed in central south-west China by the Wenchuan quake, an earthquake measuring 7.9 Moment magnitude scale.

  7. Heparin-induced thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Heparin-induced...

    In 2021 a condition resembling HIT but without heparin exposure was described to explain unusual post-vaccination embolic and thrombotic events after the Oxford–AstraZeneca COVID-19 vaccine. [20] [21] [22] It is a rare adverse event (1:1 million to 1:100,000) resulting from COVID-19 vaccines (particularly adenoviral vector vaccines). This is ...

  8. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

  9. Wuhan Institute of Biological Products - Wikipedia

    en.wikipedia.org/wiki/Wuhan_Institute_of...

    The Wuhan Institute of Biological Products (WIBP Chinese: 武汉生物制品研究所) or Wuhan Institute of Biology for short is a subsidiary of China National Pharmaceutical Group, a Chinese state-owned enterprise commonly known as Sinopharm. [1] The institute integrates production, education, research, and marketing, and operates one of the ...