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The isoelectric point (pI, pH(I), IEP), is the pH at which a molecule carries no net electrical charge or is electrically neutral in the statistical mean. The standard nomenclature to represent the isoelectric point is pH(I). [1] However, pI is also used. [2] For brevity, this article uses pI.
The Henderson–Hasselbalch equation can be used to model these equilibria. It is important to maintain this pH of 7.4 to ensure enzymes are able to work optimally. [10] Life threatening Acidosis (a low blood pH resulting in nausea, headaches, and even coma, and convulsions) is due to a lack of functioning of enzymes at a low pH. [10]
At about the same time, the Egyptian Rhind Mathematical Papyrus (dated to the Second Intermediate Period, c. 1600 BCE, although stated to be a copy of an older, Middle Kingdom text) implies an approximation of π as 256 ⁄ 81 ≈ 3.16 (accurate to 0.6 percent) by calculating the area of a circle via approximation with the octagon.
The value of each log D is then determined as the logarithm of a ratio—of the sum of the experimentally measured concentrations of the solute's various forms in one solvent, to the sum of such concentrations of its forms in the other solvent; it can be expressed as [10]: 275–8
Example Bjerrum plot: Change in carbonate system of seawater from ocean acidification.. A Bjerrum plot (named after Niels Bjerrum), sometimes also known as a Sillén diagram (after Lars Gunnar Sillén), or a Hägg diagram (after Gunnar Hägg) [1] is a graph of the concentrations of the different species of a polyprotic acid in a solution, as a function of pH, [2] when the solution is at ...
The neutral value of the pH depends on the temperature and is lower than 7 if the temperature increases above 25 °C. The pH range is commonly given as zero to 14, but a pH value can be less than 0 for very concentrated strong acids or greater than 14 for very concentrated strong bases. [2]
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This does not compute the nth decimal digit of π (i.e., in base 10). [3] But another formula discovered by Plouffe in 2022 allows extracting the nth digit of π in decimal. [4] BBP and BBP-inspired algorithms have been used in projects such as PiHex [5] for calculating many digits of π using distributed computing. The existence of this ...