Search results
Results from the WOW.Com Content Network
Phenoperidine was first synthesized in 1957 by Paul Janssen, of the company now known as Janssen Pharmaceutica, who was seeking better opioid pain-killers. [5] His two prototype drugs were methadone and pethidine , each which had been invented in 1930s by Otto Eisleb, who worked for IG Farben .
Pethidine is the most widely used opioid in labour and delivery. [16] It has fallen out of favour in some countries, such as the United States, in favour of other opioids, due to its potential drug interactions, especially with serotonergics, and its neurotoxic metabolite, norpethidine. [10]
Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales. Abbreviations are used in the list as follows: INN = International nonproprietary name
Key figures in this story—which Hughes later expanded into the nonfiction book The Hard Sell: Crime and Punishment at an Opioid Startup—included Insys founder John Kapoor, sales manager Alec ...
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and ...
Acute pain is something more than 80 million Americans fill prescriptions to treat each year, according to Vertex. As opposed to chronic pain, which can last well after an injury or illness has ...
A study by one of the manufacturers of the drug found the risk of agranulocytosis within the first week of treatment to be a 1.1 in a million, [32] versus 5.9 in a million for diclofenac. [ medical citation needed ] Therapeutic effect of metamizole on intestinal colic is attributed to its analgesic properties, with no evidence of interference ...
A fight is coming to California over whether to list one of the world's most common over-the-counter drugs as a carcinogen, echoing recent high-profile battles over things like alcohol and coffee.