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Essential tremor (ET), also called benign tremor, familial tremor, and idiopathic tremor, is a medical condition characterized by involuntary rhythmic contractions and relaxations (oscillations or twitching movements) of certain muscle groups in one or more body parts of unknown cause. [6]
Ulixacaltamide is an investigational new drug developed by Praxis Precision Medicines, designed to treat essential tremor, [1] a common neurological disorder characterized by involuntary rhythmic shaking. It functions as a selective inhibitor of T-type calcium channels, which are implicated in the abnormal neuronal activity associated with ...
Trihexyphenidyl (THP, benzhexol, trihex, marketed as Artane and others) is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used in management of Parkinson's disease. It was approved by the FDA for the treatment of Parkinson's in the US in 2003. [2] [3]
Essential tremor (sometimes inaccurately called benign essential tremor) is the most common of the more than 20 types of tremor. Although the tremor may be mild and nonprogressive in some people, in others, the tremor is slowly progressive, starting on one side of the body but affecting both sides within 3 years.
One of the first applications of HIFU was the treatment of Parkinson's disease in the 1940s. Although ineffective at the time, HIFU has the capacity to lesion pathology. A focused ultrasound system is approved in Israel, Canada, Italy, Korea and Russia to treat essential tremor, [5] neuropathic pain, [6] and Parkinsonian tremor. [7]
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