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Vaxart has been progressing in the development of an oral tablet vaccine for Norovirus, the leading cause of acute gastroenteritis globally. Norovirus significantly impacts all age groups, particularly young children and the elderly, causing millions of cases annually with substantial healthcare and economic burdens.
Gastroenteritis is usually caused by viruses; [4] however, gut bacteria, parasites, and fungi can also cause gastroenteritis. [2] [4] In children, rotavirus is the most common cause of severe disease. [10] In adults, norovirus and Campylobacter are common causes.
Sapovirus is a genetically diverse genus of single-stranded positive-sense RNA, non-enveloped viruses within the family Caliciviridae. [1] [2] Together with norovirus, sapoviruses are the most common cause of acute gastroenteritis (commonly called the "stomach flu" although it is not related to influenza) in humans and animals.
Noroviruses are a group of viruses that cause acute gastroenteritis, or an inflammation of the lining of the stomach and intestines, which leads to nausea, vomiting, diarrhea and stomach cramps ...
The 24-hour flu is usually a type of gastroenteritis, which is an inflammation of the intestines and stomach, says William Schaffner, M.D., an infectious disease specialist and professor at the ...
“Norovirus is the leading cause of vomiting and diarrhea from acute gastroenteritis in the U.S., responsible for 58% of foodborne illnesses and about 2,500 outbreaks annually,” Justman says.
Depending on the cause of the inflammation, symptoms may last from one day to more than a week. Gastroenteritis caused by viruses may last one to two days. Most people recover easily from a short episode of vomiting and diarrhea by drinking clear fluids to replace the fluid that was lost and then gradually progressing to a normal diet.
Norovirus is a common cause of epidemics of gastroenteritis on cruise ships. The CDC, through its Vessel Sanitation Program, records and investigates outbreaks of gastrointestinal illness – mostly caused by norovirus – on cruise ships with both a US and foreign itinerary; [78] there were 12 in 2015, and 10 from 1 January to 9 May 2016. An ...