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Ventriculomegaly is a brain condition that mainly occurs in the fetus when the lateral ventricles become dilated. The most common definition uses a width of the atrium of the lateral ventricle of greater than 10 mm. [1] This occurs in around 1% of pregnancies. [2]
A study of 32 normal pregnancies showed that fetal heart motion was visible at a mean human chorionic gonadotropin (hCG) level of 10,000 UI/L (range 8650–12,200). [19] Obstetric ultrasonography can also use Doppler technique on key vessels such as the umbilical artery to detect abnormal flow.
Lateral ventricles and horns The lateral ventricles connected to the third ventricle by the interventricular foramina. Each lateral ventricle takes the form of an elongated curve, with an additional anterior-facing continuation emerging inferiorly from a point near the posterior end of the curve; the junction is known as the trigone of the lateral ventricle.
The ventricles contained within the rhombencephalon become the fourth ventricle, and the ventricles contained within the mesencephalon become the aqueduct of Sylvius. Separating the anterior horns of the lateral ventricles is the septum pellucidum : a thin, triangular, vertical membrane which runs as a sheet from the corpus callosum down to the ...
During fetal development, there is a space between the two laminae called the cave of septum pellucidum that, in ninety percent of cases, disappears during infancy. [ 2 ] [ 3 ] The cavum was occasionally referred to as the fifth ventricle , but this is no longer used because the space is usually not continuous with the ventricular system . [ 4 ]
Under normal conditions, the neurons forming a germinal layer around ventricles migrate to the surface of the brain and form the cerebral cortex and basal ganglia. If this process is abnormal or disturbed it could result in the enlargement of the occipital horns of the lateral ventricles.
In vertebrates, the ventricular zone (VZ) is a transient embryonic layer of tissue containing neural stem cells, principally radial glial cells, of the central nervous system (CNS). [ 1 ] [ 2 ] The VZ is so named because it lines the ventricular system , which contains cerebrospinal fluid (CSF).
The septum pellucidum is a thin, triangular, vertical membrane separating the anterior horns of the left and right lateral ventricles of the brain. It runs as a sheet from the corpus callosum down to the fornix. During fetal development at approximately the twelfth week of gestation, a space forms between two laminae, which is the CSP. At ...