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Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels. [1] Symptoms may include chest pain, shortness of breath, leg pain, problems speaking, or problems moving parts of the body. [1] As clotting factors and platelets are used up, bleeding may occur. [1]
English: What is disseminated intravascular coagulation (DIC)? DIC's a condition where the body has both widespread clotting, leading to organ ischemia, while at the same time has a depletion of clotting factors, leading to bleeding. Sources: Aster, J.C., & Bunn, H. F. (2017).
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The process of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of ...
Hemolysis, shock, ischemia, acute respiratory distress syndrome, disseminated intravascular coagulation, [1] and acute renal failure. [2] Usual onset: Hours to months (various types of hypersensitivities reactions)of the initial drug exposure. [1] Causes: Antimicrobials, nonsteroidal anti-inflammatory drugs, antineoplastic drugs, and other ...
People with AHTR are managed with supportive care, which may include diuretics, blood pressure support, and treatment of disseminated intravascular coagulation (with fresh frozen plasma, cryoprecipitate, and platelet transfusion). [6] The use of steroids, intravenous immune-globulins or plasma exchange is not supported by evidence. [6]
The coagulation cascade is also disrupted. [4] Tissue factor that initiates the clotting cascade is produced by activated monocytes and the endothelial cells lining the blood vessels while antithrombin and fibrinolysis are impaired. [4] Disseminated intravascular coagulation (DIC) can result from the thrombin produced in the inflammatory ...
Complications following meningococcal disease can be divided into early and late groups. Early complications include: raised intracranial pressure, disseminated intravascular coagulation, seizures, circulatory collapse and organ failure. Later complications are: deafness, blindness, lasting neurological deficits, reduced IQ, and gangrene ...
Disseminated intravascular coagulation or DIC is caused by a systemic response to a specific condition including sepsis and severe infection, malignancy, obstetric complications, massive tissue injury, or systemic diseases. Disseminated intravascular coagulation is an activation of the coagulation cascade which is usually a result of an ...
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