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Peyronie's disease is a connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis. Specifically, scar tissue forms in the tunica albuginea , the thick sheath of tissue surrounding the corpora cavernosa , causing pain, abnormal curvature, erectile dysfunction , indentation, loss of girth and shortening.
Typically used to treat breast cancer, tamoxifen has been shown to prevent the progression of Peyronie’s disease in vitro when combined with the ED medication tadalafil. The applicability of ...
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen.It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous ...
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As of 2013, the majority of research investigating the use of penile traction focuses on treating the curvature and shrinkage of the penis as a result of Peyronie's disease, although some literature exists on the effects on men with short penises. [31] Scientific evidence supports some elongation by prolonged traction. [2]
Other non-FDA-approved uses include actinic keratosis, amyloidosis, Peyronie's disease, and psoriasis. Dexamethasone and betamethasone in premature labor, to enhance pulmonary maturation of the fetus. [7] Doxepin has been used to treat angiodema and severe allergic reactions due to its strong antihistamine properties. [8]
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