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  2. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    Alcohol and cocaine (for example coca wine) increase cardiovascular toxicity; [10] alcohol or depressant drugs, when taken with opioids, lead to an increased risk of overdose Opioids or cocaine taken with ecstasy or amphetamines also result in additional acute toxicity.

  3. Combined drug intoxication - Wikipedia

    en.wikipedia.org/wiki/Combined_drug_intoxication

    Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death .

  4. 12 medications you should never mix with alcohol

    www.aol.com/article/lifestyle/2019/03/04/12...

    “There aren’t many things the body does that alcohol doesn’t impact.” Here are some notable drugs, and the dangers of mixing them with booze. Watch out for the 10 signs that you’re ...

  5. Speedball (drug) - Wikipedia

    en.wikipedia.org/wiki/Speedball_(drug)

    Speedball, powerball, or over and under [1] is the polydrug mixture of a stimulant with a depressant, usually an opioid.The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl.

  6. Fentanyl in other drugs: Why do drug dealers mix them ... - AOL

    www.aol.com/fentanyl-other-drugs-why-drug...

    Fentanyl is a powerful synthetic opioid similar to morphine but 50 to 100 times more potent, according to the DEA. It is approved by the Food and Drug Administration for use as an analgesic (pain ...

  7. Weight-Loss Drugs May Help Alcohol and Opioid Addiction

    www.aol.com/lifestyle/weight-loss-drugs-may-help...

    Research hints that medications like Zepbound and Wegovy could provide new ways to treat opioid and alcohol abuse.

  8. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    The Alias flip is a very powerful mix between an Elias flip and an Ali flip. The idea is to take substances in this order to maximize the duration of 2C-E with the LSD taken one hour after 2C-E. Alcohol: Benzodiazepine: Time flip Time flipping Alcohol: Caffeine: Caffeinated alcoholic drink: Alcohol: Cannabis: Tincture of cannabis. Herb and Al ...

  9. Laudanum - Wikipedia

    en.wikipedia.org/wiki/Laudanum

    The first, from an 1870 publication, is "Best Turkey opium 1 oz., slice, and pour upon it boiling water 1 gill, and work it in a bowl or mortar until it is dissolved; then pour it into the bottle, and with alcohol of 70 percent proof 1 ⁄ 2 pt., rinse the dish, adding the alcohol to the preparation, shaking well, and in 24 hours it will be ...

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