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Most adults need 2.4 micrograms of vitamin B12 a day, although the numbers are slightly higher during pregnancy and breastfeeding. ... Causes of vitamin B12 deficiency. There are a few reasons why ...
Vitamin B12 deficiency causes symptoms like fatigue, poor memory, a swollen tongue, and canker sores. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 more ways to ...
Lack of vitamin B12 can cause megaloblastic anemia—a condition characterized by larger than normal red blood cells in a smaller than normal amount. This causes fatigue, paleness in the skin ...
Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [2] [8] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
Pernicious anemia is the most common cause of clinically evident vitamin B 12 deficiency worldwide. [14] Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [8] It more commonly affects people of northern European descent. [2]
Vitamin B 12 deficiency in pregnant women is strongly associated with an increased risk of spontaneous abortion, congenital malformations such as neural tube defects, and problems with brain development growth in the unborn child. [10] Vitamin B 12 was discovered as a result of pernicious anemia, an autoimmune disorder in which the blood has a ...
Adults need about 2.4 micrograms of B12 a day (that much can be found in one portion of salmon, canned tuna or ground beef), with pregnant and nursing women needing slightly more (2.6 and 2.8 mcg ...
Deficiency can also result from rare genetic factors, such as mutations in the MTHFR gene that lead to compromised folate metabolism. [33] [34] Cerebral folate deficiency is a rare condition in which concentrations of folate are low in the brain despite being normal in the blood. [35] Vitamin B 12 deficiency: Anemia, neurological and digestive ...
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