Search results
Results from the WOW.Com Content Network
Protamine insulin was first created in 1936 and NPH insulin in 1946. [1] It is on the World Health Organization's List of Essential Medicines. [4] NPH is an abbreviation for "neutral protamine Hagedorn". [1] In 2020, insulin isophane was the 221st most commonly prescribed medication in the United States, with more than 2 million prescriptions.
Novolin is the brand name of three distinct insulin-containing products [1] manufactured by Novo Nordisk: [2] Novolin 70/30, an insulin preparation containing mixed NPH and regular insulin, respectively; Novolin N, an insulin preparation containing NPH insulin; Novolin R, an insulin preparation containing regular insulin
Regular insulin, also known as neutral insulin and soluble insulin, is a type of short-acting medical insulin. [2] It is used to treat type 1 diabetes, type 2 diabetes, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states. [5]
The advantage of NPH is its low cost, the fact that you can mix it with short-acting forms of insulin, thereby minimizing the number of injections that must be administered, and that the activity of NPH will peak 4–6 hours after administration, allowing a bedtime dose to balance the tendency of glucose to rise with the dawn, along with a ...
[5] Examples of rapid-acting insulins (peak at ~1 hour) are: [citation needed] Insulin lispro (Humalog) Insulin aspart (Novolog) Insulin glulisine (Apidra) Examples of short-acting insulins (peak 2–4 hours) are: Regular insulin (Humulin R, Novolin R) Prompt insulin zinc (Semilente) Examples of intermediate-acting insulins (peak 4–10 hours) are:
Novo Nordisk manufactures and markets pharmaceutical products and services, specifically diabetes care medications and devices. [5] Its main product is the drug semaglutide , used to treat diabetes under the brand names Ozempic and Rybelsus and obesity under the brand name Wegovy. [ 6 ]
[1] [5] The basal level of insulin may be maintained for up to 20 hours, but the time is affected by the size of the injected dose. The changes are: removal of B30 threonine, attachment of a myristic acid tail to the B29 lysine's "tail" nitrogen. As a result, this insulin binds to serum albumin with high affinity, increasing its duration of ...
Insulin aspart, sold under the brand name NovoLog, among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [17] It is generally used by injection under the skin but may also be used by injection into a vein. [17]