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  2. Knee cartilage replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Knee_cartilage_replacement...

    It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible. Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue ...

  3. Articular cartilage repair - Wikipedia

    en.wikipedia.org/wiki/Articular_cartilage_repair

    These treatments have been shown to have positive results for patients who have articular cartilage damage. They can provide some measure of pain relief, while slowing down the accumulation of damage, or delaying the need for joint replacement (knee replacement) surgery.

  4. Autologous chondrocyte implantation - Wikipedia

    en.wikipedia.org/wiki/Autologous_Chondrocyte...

    ACI provides pain relief while at the same time slowing down the progression or considerably delaying partial or total joint replacement (knee replacement) surgery. ACI procedures aim to provide complete hyaline repair tissues for articular cartilage repair. Over the last 20 years, the procedure has become more widespread and it is currently ...

  5. Articular cartilage damage - Wikipedia

    en.wikipedia.org/wiki/Articular_cartilage_damage

    One person can have severe pain with a single small defect while another person can have very little pain with several large full thickness defects. [2] Since articular cartilage does not have a blood supply and chondrocytes (cells in articular cartilage) have limited mobility, the articular cartilage has very limited ability to heal itself.

  6. Meniscal cartilage replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Meniscal_cartilage...

    Removal of the meniscus cartilage leads to progressive, degenerative arthritis of the knee joint. Replacing the badly damaged or deficient meniscus with a meniscus transplant from a human donor restores normal knee structure and helps protect the remaining joint surfaces. Meniscal transplantation is relatively uncommon, although it is gaining ...

  7. Gene therapy for osteoarthritis - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy_for...

    In osteoarthritis, catabolic factors promote the degradation of articular cartilage and decrease the total cell content of cartilage. [17] While the body is young, anabolic factors are able to replace the lost cartilage and cartilage producing cells, however, this ability appears to decrease with age.

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