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In human genetic studies, the CHLCA is useful as an anchor point for calculating single-nucleotide polymorphism (SNP) rates in human populations where chimpanzees are used as an outgroup, that is, as the extant species most genetically similar to Homo sapiens. Despite extensive research, no direct fossil evidence of the CHLCA has been discovered.
For example, neutral human DNA sequences are approximately 1.2% divergent (based on substitutions) from those of their nearest genetic relative, the chimpanzee, 1.6% from gorillas, and 6.6% from baboons. [10] [11] Genetic sequence evidence thus allows inference and quantification of genetic relatedness between humans and other apes.
When the DNA sequences were concatenated to a single long sequence, the generated neighbor-joining tree supported the Homo-Pan clade with 100% bootstrap (that is that humans and chimpanzees are the closest related species of the four). When three species are fairly closely related to each other (like human, chimpanzee and gorilla), the trees ...
Traditionally, chimpanzees, gorillas and orangutans were grouped together, excluding humans, as pongids.Since Gray's classifications, evidence accumulating from genetic phylogeny confirmed that humans, chimpanzees, and gorillas are more closely related to each other than to the orangutan. [3]
A most recent common ancestor (MRCA), also known as a last common ancestor (LCA), is the most recent individual from which all organisms of a set are descended.The term is also used in reference to the ancestry of groups of genes rather than organisms.
The closest living relatives of humans are bonobos and chimpanzees (both genus Pan) and gorillas (genus Gorilla). [268] With the sequencing of both the human and chimpanzee genome, as of 2012 estimates of the similarity between their DNA sequences range between 95% and 99%.
Molecular anthropology, also known as genetic anthropology, is the study of how molecular biology has contributed to the understanding of human evolution. [1] This field of anthropology examines evolutionary links between ancient and modern human populations, as well as between contemporary species.
Along with the common chimpanzee, the bonobo is the closest extant relative to humans. [4] As the two species are not proficient swimmers, the natural formation of the Congo River (around 1.5–2 million years ago) possibly led to the isolation and speciation of the bonobo. Bonobos live south of the river, and thereby were separated from the ...