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  2. Midodrine - Wikipedia

    en.wikipedia.org/wiki/Midodrine

    Midodrine is a prodrug which forms the active metabolite, desglymidodrine, which is an α 1-adrenergic receptor agonist and exerts its actions via activation of α 1-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.

  3. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.

  4. Fatty liver disease - Wikipedia

    en.wikipedia.org/wiki/Fatty_liver_disease

    Fatty liver disease can occur in pets such as reptiles (particularly turtles [48]) and birds [49] as well as mammals like cats and dogs. [50] The most common cause is overnutrition. A distinct sign in birds is a misshapen beak. Fatty livers can be induced via gavage in geese or ducks to produce foie gras. Fatty liver can also be induced in ...

  5. Acute fatty liver of pregnancy - Wikipedia

    en.wikipedia.org/wiki/Acute_fatty_liver_of_pregnancy

    Liver enzymes are elevated, with the AST and ALT enzymes ranging from minimal elevation to 1000 IU/L, but usually staying in the 300-500 range. [1] Bilirubin is almost universally elevated. Alkaline phosphatase is often elevated in pregnancy due to production from the placenta, but may be additionally elevated. [4]

  6. Metabolic dysfunction–associated steatotic liver disease

    en.wikipedia.org/wiki/Metabolic_dysfunction...

    [5] [27] In some cases, it can cause symptoms related to liver dysfunction such as fatigue, malaise, and dull right-upper-quadrant abdominal discomfort. Mild yellow discoloration of the skin may occur, although this is rare. [28] MASH can severely impair liver function, leading to cirrhosis, liver failure, and liver cancer. [5]

  7. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. [ 1 ] [ 2 ] Other terms include transaminasemia , [ 3 ] and elevated liver enzymes (though they are not the only enzymes in the liver).

  8. Hy's law - Wikipedia

    en.wikipedia.org/wiki/Hy's_law

    Hy's law is a rule of thumb that a patient is at high risk of a fatal drug-induced liver injury if given a medication that causes hepatocellular injury (not Hepatobiliary injury) with jaundice. [1] The law is based on observations by Hy Zimmerman, a major scholar of drug-induced liver injury.

  9. Hepatorenal syndrome - Wikipedia

    en.wikipedia.org/wiki/Hepatorenal_syndrome

    Bleeding from esophageal varices can be a precipitant for hepatorenal syndrome in individuals with cirrhosis, and can be prevented by early diagnosis and treatment. The risk of death in hepatorenal syndrome is very high; consequently, there is a significant emphasis on the identification of patients who are at risk for HRS, and prevention of ...

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