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D-dimer (or D dimer) is a ... D-dimer increases with age. ... Likelihood ratios are derived from sensitivity and specificity to adjust pretest probability.
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In each age category over age 24, Indigenous Australians had markedly higher rates of circulatory disease than the general population: 5% vs 2% in age group 25–34, 12% vs 4% in age group 35–44, 22% vs 14% in age group 45–54, and 42% vs 33% in age group 55+.
Pregnancy is associated with an increase in fibrinogen and D-dimer levels, so this test is less useful. This should probably be mentioned in the diagnosis section. I've heard of age-adjusted D-dimer levels in the workup of PE, but I don't recall ever seeing that applied to DVT. Biosthmors 17:52, 25 May 2021 (UTC)
Principles of D-dimer testing. Fibrin degradation products (FDPs), also known as fibrin split products, are components of the blood produced by clot degeneration. [1] Clotting, also called coagulation, at the wound site produces a mass of fibrin threads called a net that remains in place until the cut is healed. As a cut heals, the clotting ...
D-dimer is highly sensitive but not specific (specificity around 50%). In other words, a positive D-dimer is not synonymous with PE, but a negative D-dimer is, with a good degree of certainty, an indication of absence of a PE. [52] A low pretest probability is also valuable in ruling out PE. [53]
A normal d-dimer range is between 0 and 200 in patients with VTE this level may reach 3000 — Preceding unsigned comment added by 92.22.2.188 17:05, 4 July 2016 (UTC) I heard 500. Jennifer H. Jones ( talk ) 10:53, 23 May 2010 (UTC) [ reply ]
References range may vary with age, sex, race, pregnancy, [10] diet, use of prescribed or herbal drugs and stress. Reference ranges often depend on the analytical method used, for reasons such as inaccuracy , lack of standardisation , lack of certified reference material and differing antibody reactivity . [ 11 ]