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Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.
The most common type of smallpox, ordinary, historically has devastated populations with a 30% death rate. The smallpox virus is transmittable through bodily fluids and materials contaminated with infected materials. Generally, face-to-face contact is required for an individual to contract smallpox as a result of an interaction with another human.
Smallpox is caused by the variola virus and is extremely contagious, for it is spread by physical contact and affects children and adults alike. Smallpox was contagious, disfiguring, and often deadly. [16] The epidemics of the disease were recurrent, devastating, and frequent. [17]
The symptoms of smallpox are rash on the skin and blisters filled with raised liquid. [ citation needed ] The disease killed an estimated 400,000 Europeans annually during the 19th century and one-third of all the blindness of that time was caused by smallpox. 20 to 60% of all the people that were infected died and 80% of all the children with ...
After the epidemic, the Hudson Bay Company implemented a territory wide vaccination program which further reduced smallpox deaths. Unfortunately, as people entered communities to vaccinate against smallpox, they brought with them other diseases that kept mortality rates high. [2] The epidemic altered power structures of impacted nations.
But the treatment's efficacy was several times demonstrated in the years which followed, when Jesty's two elder sons, exposed to smallpox, failed to catch the disease. [ 3 ] [ 4 ] [ 6 ] Interest in the prophylactic powers of cowpox virus grew and in May 1796, over 20 years after Jesty had made his inoculations, Edward Jenner began his series of ...
Most people became infected during their lifetimes, and about 30% of people infected with smallpox died from the disease, presenting a severe selection pressure on the resistant survivors. [ 29 ] In northern Japan, Ainu population decreased drastically in the 19th century, due in large part to infectious diseases like smallpox brought by ...
According to a historical account in 1884 of the 1721 smallpox outbreak, more than one sixth of people would die from smallpox naturally if not treated by inoculation. Dr. Boylston was threatened to be hanged by townsfolk because they believed that the smallpox disease was an act of God and the doctor should not interfere.
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