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A 1991 review reported that the influences of spironolactone on androgen levels in women were variable and inconsistent. [78] Spironolactone has shown no significant effect on levels of testosterone, estradiol, luteinizing hormone, and follicle-stimulating hormone in men. [146] [78]
Although useful as an antiandrogen in women, who have low testosterone levels compared to men, [193] [194] spironolactone is described as having relatively weak antiandrogenic activity. [195] [191] [196] [197] Spironolactone is a weak steroidogenesis inhibitor.
Estradiol and testosterone levels following a single intramuscular injection of 320 mg polyestradiol phosphate, a polymeric estradiol ester and prodrug, in men with prostate cancer. [158] Testosterone and luteinizing hormone levels with 100 mg/day oral cyproterone acetate in men. [159]
Dips in testosterone can cause low libido, brain fog, depression, and muscle loss, but it's pivotal you know your normal range, a doctor says.
Blood tests to check hormone levels, including testosterone, estrogen, luteinizing hormone, and anti-Mullerian hormone ... Medications like spironolactone and finasteride can also reduce androgen ...
Testosterone levels with 100 to 300 mg/day oral cyproterone acetate and low-dose oral estrogen in men. [11] The estrogen used was 0.1 mg/day diethylstilbestrol (DES), [11] which has been described as an "extremely low" dosage. [12] Levels of testosterone were decreased by about 95% with the combination and by about 61% with cyproterone acetate ...
Hone Health reports on the factors responsible for testosterone levels in men and how they are affected by age and lifestyle.
Hyperandrogenism, especially high levels of testosterone, can cause serious adverse effects if left untreated. High testosterone levels are associated with other health conditions such as obesity, hypertension, amenorrhea (cessation of menstrual cycles), and ovulatory dysfunction, which can lead to infertility.
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