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CDCA has been used as medical therapy to dissolve gallstones. [ 7 ] [ 8 ] Medical therapy with oral bile acids has been used in patients who have small cholesterol stones, and for patients with larger cholesterol gallstones who are unable or reluctant to have surgery.
Gallstones may result from increased saturation of cholesterol or bilirubin, or from bile stasis. Lower concentrations of bile acids or phospholipids in bile reduce cholesterol solubility and lead to microcrystal formation. Oral therapy with chenodeoxycholic acid and/or ursodeoxycholic acid has been used to dissolve cholesterol gallstones.
A gallstone is a stone formed within the gallbladder from precipitated bile components. [2] The term cholelithiasis may refer to the presence of gallstones or to any disease caused by gallstones, [5] and choledocholithiasis refers to the presence of migrated gallstones within bile ducts.
Outside the body it is used in experimental basis of cholagogues and is also in use to prevent and dissolve gallstones. [citation needed] In research deoxycholic acid is used as a mild detergent for the isolation of membrane associated proteins. The critical micelle concentration for deoxycholic acid is approximately 2.4–4 mM. [10]
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria.It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. [8]
Here’s how to get rid of chest congestion medically and naturally, according to experts.
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The gallbladder flush or liver cleanse is an alternative medicine practice involving fasting, followed by the ingestion of some combination of Epsom salt, olive oil, and grapefruit juice, in some cases substituted by other, similar ingredients. [1]
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