Search results
Results from the WOW.Com Content Network
Bioinformatics is the name given to these mathematical and computing approaches used to glean understanding of biological processes. Common activities in bioinformatics include mapping and analyzing DNA and protein sequences, aligning DNA and protein sequences to compare them, and creating and viewing 3-D models of protein structures.
An example of a hierarchical clustering algorithm is BIRCH, which is particularly good on bioinformatics for its nearly linear time complexity given generally large datasets. [27] Partitioning algorithms are based on specifying an initial number of groups, and iteratively reallocating objects among groups to convergence.
Pevzner is interested in new approaches to teaching computational molecular biology at both undergraduate and graduate level, [7] [8] serving as a founding instructor for the bioinformatics specialization on Coursera [9] and having written several books on bioinformatics and computational biology. [4] [10] [11] [1]
In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand its features, function, structure, or evolution. It can be performed on the entire genome, transcriptome or proteome of an organism, and can also involve only selected segments or regions ...
With a large number of bioinformatics workflow systems to choose from, [13] it becomes difficult to understand and compare the features of the different workflow systems. . There has been little work conducted in evaluating and comparing the systems from a bioinformatician's perspective, especially when it comes to comparing the data types they can deal with, the in-built functionalities that ...
An example of data integration is the use of decision support systems (DSS) based on translational bioinformatics. DSS used in this regard identify correlations in patient electronic medical records (EMR) and other clinical information systems to assist clinicians in their diagnoses.
In approaching a systems biology problem there are two main approaches. These are the top down and bottom up approach. The top down approach takes as much of the system into account as possible and relies largely on experimental results. The RNA-Seq technique is an example of an experimental top down approach. Conversely, the bottom up approach ...
Transdisciplinarity connotes a research strategy that crosses disciplinary boundaries to create a holistic approach. It applies to research efforts focused on problems that cross the boundaries of two or more disciplines, such as research on effective information systems for biomedical research (see bioinformatics), and can refer to concepts or methods that were originally developed by one ...