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2. Spironolactone - Wikipedia

   en.wikipedia.org/wiki/Spironolactone

   This is in contradiction with widespread statements that spironolactone increases free estradiol levels by displacing estradiol from SHBG. [97] [239] Spironolactone appears to cross the blood–brain barrier. [240] [241]

3. How to get a prescription without an in-person doctor visit - AOL

   www.aol.com/prescription-without-person-doctor...

   You could also inadvertently buy pills that contain completely different substances. You might think you're purchasing an antibiotic, for example, but the pill you're holding might contain a narcotic.

4. List of androgens/anabolic steroids available in the United ...

   en.wikipedia.org/wiki/List_of_androgens/anabolic...

   This is a complete list of androgens/anabolic steroids (AAS) and formulations that are approved by the FDA Tooltip Food and Drug Administration and available in the United States.

5. Potassium-sparing diuretic - Wikipedia

   en.wikipedia.org/wiki/Potassium-sparing_diuretic

   Spironolactone – most widespread use, inexpensive; Eplerenone – more selective so reduced side-effects but more expensive and less potent; Finerenone – non-steroidal, more selective and potent than spironolactone and eplerenone; Canrenone – very limited use

6. Mineralocorticoid receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/Mineralocorticoid_receptor...

   However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%

7. Antiandrogen - Wikipedia

   en.wikipedia.org/wiki/Antiandrogen

   1957: The steroidal antiandrogen spironolactone is first synthesized [219] 1960: Spironolactone is first introduced for medical use, as an antimineralocorticoid [219] 1961: The steroidal antiandrogen cyproterone acetate is first synthesized [220] 1962: Spironolactone is first reported to produce gynecomastia in men [219] [221]