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These mutations: F46T, F49L, T52F, F86L, T93P, A114G and S118T, include 5040 potential pathways for the amino acid changes required to create genetic changes in the short wavelength sensitive, or blue opsin. [9] Of the 5040 pathways, 335 have been deemed as possible trajectories for the evolution of blue opsin. [9]
The human eye, showing the iris and pupil. In 1802, philosopher William Paley called it a miracle of "design."In 1859, Charles Darwin himself wrote in his Origin of Species, that the evolution of the eye by natural selection seemed at first glance "absurd in the highest possible degree". [3]
A mutation in the HERC2 gene adjacent to OCA2, affecting OCA2's expression in the human iris, is found common to nearly all people with blue eyes. It has been hypothesized that all blue-eyed humans share a single common ancestor with whom the mutation originated. [10] [11] [12]
[56] [57] However, more recent ancient DNA research has identified human remains much older than the Neolithic period which possess the OCA2 mutation for blue eyes. It is now believed that the OCA2 allele responsible for blue eyes dates back to the migration of modern humans out of Africa roughly 50,000 years ago, and entered Europe from ...
Ojos Azules (Spanish: [ˈoxos aθˈules], 'Blue Eyes') was a breed of shorthaired [1] [2] domestic cat with unusual blue or odd eyes [1] caused by a dominant blue eye (DBE) genetic mutation. The breed came in all coat colors; however, only particolors ( bicolors and tricolors ), colorpoints , and intermediate colors with a characteristic white ...
Although infrequently seen in humans, complete heterochromia is more frequently observed in species of domesticated mammals. The blue eye occurs within a white spot, where melanin is absent from the skin and hair (see Leucism). These species include the cat, particularly breeds such as Turkish Van, Khao Manee and (rarely) Japanese Bobtail.
Discover more new species. Thousands of new species are found each year. Here are three of our most eye-catching stories from the past week. → Desert creature — a 'dynamic' predator — found ...
[79] [80] [75] A research program by geneticist Hans Eiberg and his team at the University of Copenhagen from the 1990s to 2000s investigating the origins of blue eyes revealed that a mutation in the gene OCA2 is responsible for this trait. According to them, all humans initially had brown eyes and the OCA2 mutation took place between 6,000 and ...