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The packed cell volume (PCV) can be determined by centrifuging EDTA-treated or heparinized blood in a capillary tube (also known as a microhematocrit tube) at 10,000 RPM for five minutes. [12] This separates the blood into layers. The volume of packed red blood cells divided by the total volume of the blood sample gives the PCV.
Polycythemia is defined as serum hematocrit (Hct) or hemoglobin (HgB) exceeding normal ranges expected for age and sex, typically Hct >49% in healthy adult men and >48% in women, or HgB >16.5 g/dL in men or >16.0 g/dL in women. [8] The definition is different for neonates and varies by age in children. [9] [10]
A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood.The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells).
References range may vary with age, sex, race, pregnancy, [10] diet, use of prescribed or herbal drugs and stress. Reference ranges often depend on the analytical method used, for reasons such as inaccuracy , lack of standardisation , lack of certified reference material and differing antibody reactivity . [ 11 ]
Normal values of ESR have been quoted as 1 [24] to 2 [25] mm/h at birth, rising to 4 mm/h 8 days after delivery, [25] and then to 17 mm/h by day 14. [24] Typical normal ranges quoted are: [6] Newborn: 0 to 2 mm/h; Neonatal to puberty: 3 to 13 mm/h, but other laboratories place an upper limit of 20. [26]
Red blood cell concentrates, also known as red cell concentrates or packed red blood cells, are red blood cells that have been separated for blood transfusion. [1] A red blood cell concentrate typically has a haematocrit of 0.50 – 0.70 L/L and a volume between 250 and 320 mL.
in a woman at or near term in her pregnancy, the mean volume of maternal red blood cells is approximately 1800 ml; the mean fetal hematocrit is 50%; and at stillbirth , the mean fetal blood volume is 150 m l k g {\displaystyle 150{\frac {ml}{kg}}}
In patients with anemia, it is the MCV measurement that allows classification as either a microcytic anemia (MCV below normal range), normocytic anemia (MCV within normal range) or macrocytic anemia (MCV above normal range). Normocytic anemia is usually deemed so because the bone marrow has not yet responded with a change in cell volume.