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A bone tumor is an abnormal growth of tissue in bone, traditionally classified as noncancerous (benign) or cancerous (malignant). [1] [4] Cancerous bone tumors usually originate from a cancer in another part of the body such as from lung, breast, thyroid, kidney and prostate. [1] There may be a lump, pain, or neurological signs from pressure. [1]
An osteosarcoma (OS) or osteogenic sarcoma (OGS) (or simply bone cancer) is a cancerous tumor in a bone.Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid.
Enchondroma is a type of benign bone tumor belonging to the group of cartilage tumors. [1] [2] There may be no symptoms, [3] or it may present typically in the short tubular bones of the hands with a swelling, pain or pathological fracture.
[1] [2] The tumors take the form of cartilage-capped bony projections or outgrowth on the surface of bones . [3] [4] It is characterized as a type of overgrowth that can occur in any bone where cartilage forms bone. Tumors most commonly affect long bones about the knee and in the forearm.
Bone cancer is caused when cancer cells form in the bones and creates malignant growths, which can be fatal. Of note, primary bone cancer (e.g. osteosarcoma) is relatively uncommon. Most people who are reported as having "bone cancer" actually have another cancer that has "metastasized" or spread to the bone.
Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing sarcoma are rare; the most common bone tumor is a metastasis. [1] Bone metastases can be classified as osteolytic, osteoblastic, or both. Unlike hematologic malignancies which originate in the blood and form non-solid tumors, bone metastases generally arise from ...
Before the micrometastases colonize at a distant site, the tumor cells can be found in the bone marrow or peripheral blood. [3] Tumor cells found in the bone marrow are known as disseminated tumor cells (DTCs), and those found in the peripheral blood are known as circulating tumor cells (CTCs). These cells have successfully left the primary ...
A non-ossifying fibroma (NOF) is a benign bone tumor of the osteoclastic, giant cell-rich tumor type. [1] It generally occurs in the metaphysis of long bones in children and adolescents. [2] Typically, there are no symptoms unless there is a fracture. [2]
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