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NP-40 (also known as Tergitol-type NP-40 and nonyl phenoxypolyethoxylethanol [1]) is a commercially available detergent with CAS Registry Number 9016-45-9. NP-40 is an ethoxylated nonylphenol for non-ionic surfactants and can act as emulsifier and demulsifier agent.
Nonidet P-40 is a nonionic, non-denaturing detergent.Its official IUPAC name is octylphenoxypolyethoxyethanol.. Nonidet P-40 is sometimes abbreviated as NP-40, but should not be confused with a different detergent by the same name NP-40, nonylphenoxypolyethoxyethanol of the Tergitol NP series of Dow Chemicals.
IGEPAL CA-630 has HLB of 13.4, similar to that of Triton X-100 (13.4) and thus belongs to the detergent range (HLB 13-15); this is significantly less than 17.8 of tergitol NP-40 or 16.7 of Polysorbate 20 (also known as Tween 20), which both belong in the solubilizer range (15-18) of HLB. [2] Ca-630 is completely miscible with water.
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To make NPEs, manufacturers treat NP with ethylene oxide under basic conditions. [12] Since its discovery in 1940, nonylphenol production has increased exponentially, and between 100 and 500 million pounds of nonylphenol are produced globally every year, [ 12 ] [ 16 ] meeting the definition of High Production Volume Chemicals .
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