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  2. Glucosamine - Wikipedia

    en.wikipedia.org/wiki/Glucosamine

    As the formation of glucosamine-6-phosphate is the first step for the synthesis of these products, glucosamine may be important in regulating their production; however, the way that the hexosamine biosynthesis pathway is actually regulated, and whether this could be involved in contributing to human disease remains unclear.

  3. Clinical trials on glucosamine and chondroitin - Wikipedia

    en.wikipedia.org/wiki/Clinical_trials_on...

    A significant amount of research has been performed on glycosaminoglycans, especially glucosamine and chondroitin, for the treatment of arthritis.These compounds are commonly marketed as nutritional supplements and numerous 'soft therapeutic claims' are made about their health benefits - especially in aging populations. [1]

  4. Polysulfated glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Polysulfated_glycosaminoglycan

    Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]

  5. Streptozotocin - Wikipedia

    en.wikipedia.org/wiki/Streptozotocin

    Streptozotocin is a glucosamine-nitrosourea compound. As with other alkylating agents in the nitrosourea class, it is toxic to cells by causing damage to the DNA, though other mechanisms may also contribute. DNA damage induces activation of PARP which is likely more important for diabetes induction than the DNA damage itself. [4]

  6. Chondroitin sulfate - Wikipedia

    en.wikipedia.org/wiki/Chondroitin_sulfate

    The bioavailability of chondroitin sulfate ranges from 15% to 24% of the orally administered dose. More particularly, on the articular tissue, Ronca et al. [ 19 ] reported that chondroitin sulfate is not rapidly absorbed in the gastro-intestinal tract and a high content of labeled chondroitin sulfate is found in the synovial fluid and cartilage.

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