Search results
Results from the WOW.Com Content Network
List of sulfonamides; Author of The Demon Under the Microscope, a history of the discovery of the sulfa drugs; A History of the Fight Against Tuberculosis in Canada (Chemotherapy) Presentation speech, Nobel Prize in Physiology and Medicine, 1939; The History of WW II Medicine "Five Medical Miracles of the Sulfa Drugs".
Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs. The original antibacterial sulfonamides are synthetic (nonantibiotic) antimicrobial agents that contain the sulfonamide group.
Relatively speaking this group is unreactive. Because of the rigidity of the functional group, sulfonamides are typically crystalline; for this reason, the formation of a sulfonamide is a classic method to convert an amine into a crystalline derivative which can be identified by its melting point. Many important drugs contain the sulfonamide group.
Pages in category "Sulfonamides" The following 200 pages are in this category, out of approximately 224 total. This list may not reflect recent changes.
[26] [27] Sulfonamides, sulfinamides and sulfenamides, with formulas R−SO 2 NR′ 2, R−S(O)NR′ 2, and R−SNR′ 2, respectively, each have a rich chemistry. For example, sulfa drugs are sulfonamides derived from aromatic sulfonation. Chiral sulfinamides are used in asymmetric synthesis, while sulfenamides are used extensively in the ...
Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group. [1] Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to ...
Sulfonylureas contain a central S-arylsulfonylurea structure with a p-substituent on the phenyl ring (R 1) and various groups terminating the urea N ′ end group (R 2). Chemically, this functionality can be easily installed by reacting aryl sulfonamides (R 1 —C 6 H 4 —SO 2 NH 2) with isocyanates (R 2 —NCO).
Pages in category "Sulfonamide antibiotics" The following 42 pages are in this category, out of 42 total. This list may not reflect recent changes. *