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  2. DNA polymerase - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase

    A DNA polymerase is a member of a family of enzymes that catalyze the ... Unlike other DNA polymerases, the structure and mechanism of the DP2 catalytic core ...

  3. DNA polymerase III holoenzyme - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase_III_holoenzyme

    DNA polymerase III synthesizes base pairs at a rate of around 1000 nucleotides per second. [3] DNA Pol III activity begins after strand separation at the origin of replication. Because DNA synthesis cannot start de novo, an RNA primer, complementary to part of the single-stranded DNA, is synthesized by primase (an RNA polymerase): [citation ...

  4. DNA polymerase I - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase_I

    DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication. Discovered by Arthur Kornberg in 1956, [1] it was the first known DNA polymerase (and the first known of any kind of polymerase). It was initially characterized in E. coli and is ubiquitous in prokaryotes.

  5. DNA polymerase II - Wikipedia

    en.wikipedia.org/wiki/DNA_polymerase_II

    DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-dependent DNA polymerase encoded by the PolB gene. [1] DNA Polymerase II is an 89.9-kDa protein and is a member of the B family of DNA polymerases. It was originally isolated by Thomas Kornberg in 1970, and characterized over the next few years.

  6. Taq polymerase - Wikipedia

    en.wikipedia.org/wiki/Taq_polymerase

    Taq polymerase exonuclease is a domain found in the amino-terminal of Taq DNA polymerase I (thermostable). It assumes a ribonuclease H-like motif. The domain confers 5'-3' exonuclease activity to the polymerase. [17]

  7. Polymerase - Wikipedia

    en.wikipedia.org/wiki/Polymerase

    Structure of Taq DNA polymerase. In biochemistry, a polymerase is an enzyme (EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids. DNA polymerase and RNA polymerase are used to assemble DNA and RNA molecules, respectively, by copying a DNA template strand using base-pairing interactions or RNA by half ladder replication.

  8. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    The double-stranded structure of DNA provides a simple mechanism for DNA replication. Here, the two strands are separated and then each strand's complementary DNA sequence is recreated by an enzyme called DNA polymerase. This enzyme makes the complementary strand by finding the correct base through complementary base pairing and bonding it onto ...

  9. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    The structure of the DNA double helix (type B-DNA). The atoms in the structure are colour-coded by element and the detailed structures of two base pairs are shown in the bottom right. DNA exists as a double-stranded structure, with both strands coiled together to form the characteristic double helix.

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