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  2. Temozolomide - Wikipedia

    en.wikipedia.org/wiki/Temozolomide

    Temozolomide is an alkylating agent used to treat serious brain cancers; most commonly as second-line treatments for astrocytoma and as the first-line treatment for glioblastoma. [4] [6] [7] Olaparib in combination with temozolomide demonstrated substantial clinical activity in relapsed small cell lung cancer. [8] It is available as a generic ...

  3. US FDA approves Servier's brain tumor treatment - AOL

    www.aol.com/news/us-fda-approves-serviers-brain...

    The drug, branded as voranigo, is used to treat a form of brain cancer, called Grade 2 IDH-mutant glioma, in patients who have had surgery. Gliomas, types of brain cancer that can hinder normal ...

  4. Chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy

    This is because the brain has an extensive system in place to protect it from harmful chemicals. Drug transporters can pump out drugs from the brain and brain's blood vessel cells into the cerebrospinal fluid and blood circulation. These transporters pump out most chemotherapy drugs, which reduces their efficacy for treatment of brain tumors.

  5. Brain tumor - Wikipedia

    en.wikipedia.org/wiki/Brain_tumor

    Radiotherapy: [60] the most commonly used treatment for brain tumors; the tumor is irradiated with beta, x rays or gamma rays. Chemotherapy: [60] a treatment option for cancer, however, it is not always used to treat brain tumors as the blood–brain barrier can prevent some drugs from reaching the cancerous cells.

  6. Glioblastoma - Wikipedia

    en.wikipedia.org/wiki/Glioblastoma

    The brain is susceptible to damage from conventional therapy. The brain has a limited capacity to repair itself. Many drugs cannot cross the blood–brain barrier to act on the tumor. Treatment of primary brain tumors consists of palliative (symptomatic) care and therapies intended to improve survival.

  7. Lomustine - Wikipedia

    en.wikipedia.org/wiki/Lomustine

    It is a highly lipid-soluble drug, [3] thus it crosses the blood–brain barrier. This property makes it ideal for treating brain tumors, which is its primary use, although it is also used to treat Hodgkin lymphoma as a second-line option. [4] It has also been used in veterinary practice as a treatment for cancers in cats and dogs. [5]

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