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Benzyl alcohol is used effectively for treating lice infestations as the active ingredient in lotion shampoo with 5% benzyl alcohol. [13] Benzyl alcohol is an ingredient used in the manufacture of soaps, topical creams, skin lotions, shampoos, and facial cleansers and is popular due to its anti-bacterial and anti-fungal properties.
2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Cofsils , Strepsils , Lorsept, and Gorpils.
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk .
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The symptoms caused by benzyl alcohol exposure include respiratory failure, hypotension, renal failure, severe metabolic acidosis, hematologic abnormalities, convulsions, paralysis gradual neurologic deterioration, cardiovascular collapse, sudden onset of gasping respiration, skin changes and vasodilation.
The first four seem to be involved in the hydroxylation of toluene to benzyl alcohol. CYP2E1 seems to be the primary enzyme in the hydroxylation of toluene, accounting for roughly 44% of toluene metabolism; [ 1 ] however, there is a great deal of ethnic variability, in the Finnish population for example the primary enzyme is CYP2B6 .
A 2020 systematic review and meta-analysis concluded that there is no definitive link between alcohol-based mouthwash use and the risk of oral cancer. [21] This should not be confused with the fact that alcohol consumption at any quantity is a risk factor for alcohol and cancer such as cancers of the mouth, esophagus, pharynx and larynx. [22]
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