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Some of these uses include acne, seborrhea, hirsutism, and pattern hair loss in women. [38] Spironolactone is used for the treatment of hirsutism in the United States. [39] High doses of spironolactone, which are needed for considerable antiandrogenic effects, are not recommended for men due to the high risk of feminization and other side effects.
“Just as much as the GLP-1s are a diabetes drug and a weight loss medicine, they are brain drugs, too,” says Rekha Kumar, MD, an endocrinologist at New York-Presbyterian and Weill Cornell ...
Experts agree that eating wholesome, healthy meals, reducing calories, and increasing physical activity are the best ways to lose weight and keep it off long-term. Still, many people turn to ...
As GLP-1 weight-loss injectables grow in popularity, some people are wondering if they can skip the drugs — which impact satiety — to indulge in holiday meals.
Androgen receptor antagonistic potency of spironolactone, cyproterone acetate, and flutamide in castrated male rats treated with exogenous testosterone (as measured by inhibition of androgen-dependent ventral prostate weight). [27] Spironolactone is an antagonist of the AR, the biological target of androgens like testosterone and DHT.
Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...
Failing to do that could result in poor performance reviews, low ratings from insurance companies or being denied reimbursement if they refer patients to specialized care. Another issue, says Kimberly Gudzune, an obesity specialist at Johns Hopkins, is that many doctors, no matter their specialty, think weight falls under their authority.
The success of weight loss drugs like Ozempic heavily relies on the effect that they have in your brain, too, according to doctors. This is how GLP-1s impact your mind. ... per a 2020 review in ...