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Dexmedetomidine, sold under the brand name Precedex among others, is a medication used for sedation. [4] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. [10] [11] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar disorder. [5]
However, since its introduction to the market in 2013, the drug’s efficacy in cats has been subject to extensive study. The post Apoquel for Cats: Uses, Dosage, & Side Effects appeared first on ...
Once your beloved cat reaches 10 years or older, they are typically considered to be a senior. As our kitties enter their golden years, they may need adjustments in how they are cared for by their ...
Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.
This occurs due to profound hypotension caused by reversal of the alpha 1 effects while the reflex bradycardia is still in effect.). There is a low rate of side effects, largely due to atipamezole's high specificity for the α 2-adrenergic receptor. Atipamezole has a very quick onset, usually waking an animal up within 5 to 10 minutes.
Cats who are younger/middle-aged (i.e. those less than 10 years old) Indoor cats and/or cats who are unable express natural feline behaviour (e.g. hunting) [ 16 ] Cats fed a dry food diet who may be inadequately hydrated [ 16 ] [ 17 ]
They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives, like xylazine, medetomidine and dexmedetomidine. Alpha-2 blockers increase noradrenaline release.
[2] [4] [6] [7] The syndrome usually appears in cats after they've reached maturity, with most cases first arising in cats between one and five years old. [1] [2] [4] The condition is most commonly identified by frantic scratching, biting or grooming of the lumbar area, generally at the base of the tail, and a rippling or rolling of the dorsal ...