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Paraphrenia is often associated with a physical change in the brain, such as a tumor, stroke, ventricular enlargement, or neurodegenerative process. [4] Research that reviewed the relationship between organic brain lesions and the development of delusions suggested that "brain lesions which lead to subcortical dysfunction could produce delusions when elaborated by an intact cortex".
John Haslam (1764–1844) was an English apothecary, physician and medical writer, known for his work on mental illness.Haslam's case study of James Tilly Matthews is the earliest detailed description of paranoid schizophrenia.
The first of these, in 1884-1885 was what was then diagnosed as dementia praecox (later known as paranoid schizophrenia or schizophrenia, paranoid type). He described his second mental illness , from 1893 to 1902, making also a brief reference to the first disorder from 1884 to 1885, in his book Memoirs of A Nervous Illness ( German ...
The result means that, of these, 21 will not be identified as having schizophrenia by use of FRS (43% of 48). Then, of the 52 people really without schizophrenia, 10 may be incorrectly diagnosed with schizophrenia by the FRS. Diagnosis of schizophrenia from other types of psychosis Sensitivity 58.0 (50.3, 65.3) Specificity 74.7 (85.2, 82.3)
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
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The prognosis of schizophrenia is varied at the individual level. In general it has great human and economics costs. [ 1 ] It results in a decreased life expectancy of 12–15 years primarily due to its association with obesity , little exercise, and smoking , while an increased rate of suicide plays a lesser role. [ 1 ]
The Oxford–Liverpool Inventory of Feelings and Experiences (O-LIFE) is a questionnaire for measuring psychosis-proneness, principally schizotypy. [1] It was introduced in 1995 and has since been used in a variety of experimental and clinical studies.