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The result means that, of these, 21 will not be identified as having schizophrenia by use of FRS (43% of 48). Then, of the 52 people really without schizophrenia, 10 may be incorrectly diagnosed with schizophrenia by the FRS. Diagnosis of schizophrenia from other types of psychosis Sensitivity 58.0 (50.3, 65.3) Specificity 74.7 (85.2, 82.3)
Paraphrenia is often associated with a physical change in the brain, such as a tumor, stroke, ventricular enlargement, or neurodegenerative process. [4] Research that reviewed the relationship between organic brain lesions and the development of delusions suggested that "brain lesions which lead to subcortical dysfunction could produce delusions when elaborated by an intact cortex".
The first of these, in 1884-1885 was what was then diagnosed as dementia praecox (later known as paranoid schizophrenia or schizophrenia, paranoid type). He described his second mental illness , from 1893 to 1902, making also a brief reference to the first disorder from 1884 to 1885, in his book Memoirs of A Nervous Illness ( German ...
The International Classification of Diseases classifies delusional disorder as a mental and behavioural disorder. [15] Diagnosis of a specific type of delusional disorder can sometimes be made based on the content of the delusions, to wit, the Diagnostic and Statistical Manual of Mental Disorders (DSM) enumerates seven types:
Subtypes of schizophrenia – classified as paranoid, disorganized, catatonic, undifferentiated, and residual – were difficult to distinguish and are no longer recognized as separate conditions by DSM-5 (2013) or ICD-11. [265] [266] [267]
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Simple-type schizophrenia is a sub-type of schizophrenia included in the International Classification of Diseases , [1] in which it is classified as a mental and behaviour disorder. [2] It is not included in the current Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ) or the upcoming ICD-11 , [ 3 ] effective 1 January 2022. [ 4 ]
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.